Number of therapeutic drugs that can be delivered through nano methods is increasing with the inclination of pharmaceutical companies

Industry Insights

The global nanomedicine market size was worth USD 138.9 billion in 2016 which is anticipated to grow at a CAGR of more than 9.8% during the forecast period. Factors such as technological advancements along with significant applications in the prophylaxis of acute and chronic diseases, prevention intervention, and early disease diagnosis are accountable for progress of this industry. Miniaturization of bigger chemicals and structures at nanometric scale enables the modernization in drug administration thus leading to growth in nanotechnology market for healthcare industry. 

Advancements in nanorobotics due to the escalation in funding from the government bodies are accountable to persuade potential to the nanomedicine market. Moreover, nanorobotics engineering projects which are targeting only the cancer cells without affecting the contiguous tissues is expected to promote progress through to 2025.

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Factors such as the capability of nanotechnology to assist in both therapeutic and diagnostics sector simultaneously are accountable for a large number of researches which are undergoing in this sector. Moreover, application of DNA origami in the healthcare is accountable for the projected CAGR.

Furthermore, pipeline products based on the nano-molecules and related technologies are expected to promote the progress over the forecast period. Other factors such as, presence of number of products in phase II trial of clinical development and personalized treatment option is also available which is accountable for the development of nanotechnology for health care in the coming years.

Product Insights

In 2016, the foremost share was accounted by therapeutics owing to the existence of various products such as drug delivery systems, devices, and drugs falling in this classification. Number of therapeutic drugs that can be delivered through nano methods is increasing with the inclination of pharmaceutical companies towards these research activities. 

Nanotechnology is a promising technology which delivers drugs at the site of action with an enhanced cellular penetration and reduced toxicity. The aforementioned fact, is supportive for the estimated share of therapeutics segment. Moreover, development of innovative delivery products by using various kinds of nanoparticles is anticipated to boost the market growth.

Application Insights

Based on application, the segment incorporates cardiology, infectious diseases, oncology, and other applications. In 2016, oncology segment dominated with approximately 47% revenue share. 

Rise in the R&D and funding activities in this segment is attributive for the larger share of this segment. Moreover, continuous increase in the incidence of oncology diseases is attributive for the development of nanotechnology based products for cancer eradication.

Cardiology is expected to witness fastest growth as a result of higher demand in the projected period due to several opportunities such as implants for tissue regeneration, nanostructured stents, and therapeutic nano-vectors.

Nanomolecule Type Insights

The capability of nanoparticles to get linked with the chemical moieties in different forms such as scaffolds aids in performing different functions. Moreover, application of nanoparticles for active targeting by linking it to cell receptor’s ligands is expected to drive progress potentially nanotechnology.

Metal and metal oxide is expected to witness substantial demand due to its widespread utilization in diagnostics. These nanoparticles enable diagnosis through the unique properties of different metals and metal oxides.

Dendrimers and the inorganic nanoparticles are also anticipated to grow at a potential rate in the coming years as consequence of research carried out in these segments. Furthermore, rising inclination of physicians towards nanodevices for monitoring and prognosis is anticipated to boost demand in the coming years.

Regional Insights

The nanomedicine market was dominated by North America with over 42% of revenue share due to escalating partnerships between nanomedicine startups and enterprises. Moreover, assistance from government organizations along with higher R&D expenditure is accountable for the largest share of the province in this sector.

Asia Pacific is anticipated to witness fruitful growth owing to factors such as rising demand for prophylaxis of life-threatening diseases and increase in a number of research grants. The escalation in a number of venture capital financiers and rising international research associations are expected to promote the nanomedicine growth in this region.

Competitive Insights

Several vital players are functioning in this market such as Teva Pharmaceutical Industries Ltd, Nanosphere, Inc., Celegene Corporation, Ablynx NV, GE Healthcare, Arrowhead Research, and Combimatrix Corp. These players are engaged in attaining the U.S. FDA approvals in order to enhance their revenue share. 

Rising penetration of the companies in diverse segments with respect to nanotechnology in order to replace the conventional options of treatment and diagnosis is anticipated to lead in growth in the coming years. Market entities are engaged in collaborations with research institution and academic organizations in order to carry out active research. 

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Doxorubicin Market is estimated to grow at a significant CAGR of 6.4% over the forecast period

Global Doxorubicin Market is expected to reach USD 1.38 billion by 2024. Doxorubicin is an anticancer chemotherapy drug, a generic name for the trade name drug Rubex® and Adriamycin®. It is injected into a vein. It is an essential medicine on the World Health Organization's List, the safest and effective medicines needed in a health system. The Doxorubicin Market is estimated to grow at a significant CAGR of 6.4% over the forecast period as the scope and its applications are rising enormously across the globe.

Growing presence of cancer patients across the globe, increasing number of manufacturers in the market to control the shortage of drugs, and developed laboratories with the latest technological equipment’s for research are documented as the major driving factors for Doxorubicin Market. Also, inclusion of doxorubicin drug in several applications like neuroblastoma, AIDS-related Kaposi Sarcoma, and others may boost the overall market in the years to come.

However, side effects of drugs and high cost of treatment are the factors that may restrain overall market growth in the coming years. Doxorubicin Industry is segmented based on formulation, cancer type, distribution channel, and region. Doxorubicin injection and lyophilized doxorubicin powder are the formulations that could be explored in Doxorubicin in the forecast period.

There are several types of cancer like Leukemia, Breast Cancer, Stomach Cancer, Prostate Cancer, Bladder Cancer, Ovary Cancer, Lung Cancer, and others that could be explored in Doxorubicin in the forecast period. Breast cancer and prostate cancer accounted for the majority market share in 2017 and are estimated to lead the overall market in the years to come. This may be because of rising number of people suffering from breast and prostate cancer.

The market may be categorized based on distribution channel like E-Commerce, Retail Pharmacies, Hospitals Pharmacies, and others could be explored in the forecast period. Globally, North America accounted for the substantial market share of Doxorubicin in 2017 and is estimated to continue with its dominance in the near future. The reason behind the overall market growth could be presence of developed healthcare infrastructure, presence of key manufacturers in the region, and increasing number of cancer epidemiology. The United States is a major consumer of Doxorubicin in this region.

Europe and the Asia Pacific are also estimated to have a positive influence on the future growth. Europe is the second largest region with significant market share. However, Asia Pacific is estimated to grow at the fastest pace in the foremost period. The aspects that may be ascribed to the growth comprise rising pharmaceutical market, developing healthcare infrastructure and growing occurrence of cancer mainly gastric cancer and lung cancer among population. The developing countries like India, Japan, and China are the major consumers of Doxorubicin in this region.

The key players of Doxorubicin Market are Synbias Pharma, Pfizer Inc., MicroBiopharm Japan Co., Ltd., Johnson & Johnson Services, Inc., Teva Pharmaceutical Industries Ltd., Sun Pharmaceutical Industries Ltd., and Meiji Seika Pharma Co., Ltd. These players are concentrating on inorganic growth to sustain themselves amongst fierce competition. As companies all over the world have to believe that alliance with a market would permit them proportional market existence and authority to declare the leadership position.

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Growing emphasis of Public Health Services on the improvement of examinations and processes

The global Biodefense Market was appreciated at US$ 9.5 Billion in the year 2015. It is estimated to develop at a substantial CAGR for the duration of the prediction. The market is projected to observe development due to technical progressions in detection techniques of pathogen, in the division of forensics. The technical progressions include the progressive indicator hardware, nanotechnology, chips of genetic factor, and management of database systems.

The increasing production of inoculations, speedy measures of analytics, superior therapies of discovery &forensics and prophylactics are amongst the essential issues likely to reinforce the competences of biodefense throughout the world above the prediction period. Money management done by the provincial administrations in developed markets for the readiness of biodefense, like in Europe and the U.S.A. are expected to empower the development of the market above the prediction period.

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Growing danger of bioterrorism and existence of promising government inventiveness in contradiction to bio-terrorism are important reasons that will motivate the international market in the approaching years. The growing emphasis of Public Health Services on the improvement of examinations and processes to classify bio threat mean motivating the market for biodefense.

The Biodefense market on the source of Type of Product shows the Manufacture, Profits, Price, Market stake and Development percentage of respective category. The market is divided into Radiation/Nuclear Defense, Smallpox, Botulism, Anthrax, and others. The subdivision of Anthrax was the biggest product type. It was responsible for a stake of more than 31.3% during the year 2015.The Anthrax was tracked by smallpox. As of now, it is wiped out all over the world, thanks to worldwide vaccination drive.

The Biodefense market on the source of Area with respect to Trades in terms of intake, Profits, Market stake and Development percentage in these areas, for the duration of the prediction could span North America [U.S.A, Canada], Europe [Germany, U.K.], Asia Pacific [Japan, China], Latin America [Mexico, Brazil], Middle East & Africa [South Africa].

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By the source of geography, Asia Pacific is projected to appear as an important market for biodefense owing to the growing acceptance of specific diagnostic apparatuses and speedy progression of the biotechnology business. Asia Pacific is projected to witness an important demand because of rushing funds in the R&D area. Japan and Australia are the most developed markets of Asia Pacific.

The widespread inoculation manufacturing amenities present throughout Japan combined with the existence of classy healthcare set-up in the nation contribute to its robust market situation. Australia governs the Communicable Disease Network Australia [CDNA]. It works in the direction of neutralizing eruptions of sickness and the thoughtful discharge of hazardous pathogens.

North America is the biggest market for biodefense owing to superior laboratory proficiencies and better-quality substructure for rising alarm for the hazard to fitness. Europe is the subsequent biggest market for biodefense. Additional areas for example the Latin America and Middle East are expected to be important areas for biodefense owing to the increasing presence of foremost biotechnology companies in these areas

The statement revises Trades in terms of intake of Biodefense in the market; particularly in North America, Europe, Asia Pacific, Latin America and Middle East & Africa. It concentrates on the topmost companies operating in these regions. Some of the important companies operating in the field at the international level are Alnylam Pharmaceuticals, Inc., Achaogen, Inc., Cleveland Bio Labs, Ichor Medical Systems, SIGA Technologies, Bio Solutions, Inc., Pharm Athene, Inc., Nano therapeutics, Inc., Bavarian Nordic, DynPort Vaccine Company, LLC,Elusys Therapeutics, Inc., Dynavax Technologies Corporation, Emergent Bio Solutions, Inc.,and Xoma Corporation.

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Antifungal agents presently available for the treatment of complete fungal infections

Global Antifungal Drugs Market is anticipated to reach USD 12.6 billion by 2025. Anti-fungal drugs, as the name suggests, are used to cure fungal infections. Common fungal infections such as ringworm, fungal nail infection, and vaginal infection typically occur on the external surface of the body, although specific fungal invasive infections occur in an internal body organs such as brain and lungs.

The factors that propel the growth of the Antifungal Drugs Market include increasing occurrence of fungal infections across the globe, increasing consciousness, and ongoing research and development in anti-fungal drugs. On the other hand, there are factors that may hamper the growth of the market including occurrence of counterfeit drugs and resistance towards antifungal drugs.

The antifungal agents presently available for the treatment of complete fungal infections are: amphotericin B and lipid formulations of amphotericin B, azoles,5-fluorocytosine, ketoconazole, miconazole, fluconazole and itraconazole. Antifungal Drugs Industry is anticipated to grow at a significant CAGR in the upcoming period as the scope, product types, and its applications are increasing across the globe. The industry may be explored by drug type, dosage form, infection type, therapeutic indications and geography.

Antifungal Drugs Market may be explored by drug type as Azoles may further include (Thiazoles, Voricanazole, Imidazole’s, and Others), Echinocandins may further include (Anidulafungin, Micafungin, Caspofungin, and Others), Allylamines may further include (Naftifine, Terbinafine, Butenafine, and Others), and Polyenes may further include (Amphotericin B, Candicidin, Natamycin, Hamycin, and Others). The “Azoles” segment led the Antifungal Drugs Industry in 2015 and is anticipated to maintain its dominance by 2025. The key factor that could be attributed to the growth may include composition of important agents such as Vfend, Diflucan, and Noxafil, and extensive usage in the treatment of candidemia, blastomycosis, systemic candidiasis and ocular fungal infections.

The dosage form that could be explored in the Antifungal Drugs Industry include Drugs, Ointments, Powders, and Others. The industry could be explored based on infection type as Systemic Antifungal Infections, and superficial Antifungal Infections. The market may be analyzed by therapeutic indications as Dermatophytosis, Aspergillosis, Candidiasis, and Others. The “Dermatophytosis” segment led the market in 2015 and is anticipated to maintain its dominance by 2025. The factors that could be attributed to the growth include increasing occurrence of skin infections in kids, and rise in the incidence of opportunistic fungal infections that will eventually surge the Dermatophytosis segment in the forecast period.

North America accounted for the major share of the Antifungal Drugs Market Size in 2015 and will continue to lead in the forecast period. The factors that could be attributed to the growth include high patient consciousness levels, and R&D strength pertaining to new drug development.

Some of the key players that fuel the growth of the Antifungal Drugs Industry comprise Sigma-Aldrich Corporation, Astellas Pharma, Inc., Agilent Technologies, Inc., Inc. (a subsidiary of Danaher Corporation), Beckman Coulter, Kramer Laboratories, Valeant Pharmaceuticals International, Inc., Tecan Group, and Basilea Pharmaceutical Ltd. The leading companies are taking up partnerships, mergers and acquisitions, and joint ventures in order to boost the inorganic growth of the industry.

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Peptides are used in drugs to improve the patient’s medical condition

Global Peptide Therapeutics Market is predicted to reach USD 48.04 billion by 2025 owing to rise in demand for efficient & speedy treatment of cancer and other lifestyle-related disorders. Peptides are the naturally occurring biological molecules that are used in drugs to improve the patient’s medical condition. They are highly safe and effective due to which they are widely accepted by physicians and patients for treating several ailments.

In the medical practice, they are ideal for diabetes, infectious diseases, several type of cancers, cardiovascular and other medical conditions. Peptides are highly modifiable and versatile in comparison to other drugs, which make them highly profitable to sponsors. Due to their feature of versatility, they are used in multiple medical conditions that leads to higher penetration of peptide therapeutics industry. Apart from therapeutics effects, the market is also gaining attraction due to comparatively easy marketing approval and familiarity.

Along with the growing prevalence of cardiovascular disorders and cancers, the increasing research & development activities and rich peptide therapeutics pipeline are predicted to support the growth of the market in near future. The patent expiration of various peptide drugs in future is expected to create ample opportunities for the market contributing to its growth at a significant rate.

Peptide therapeutics have application in CNS (Central Nervous System) disorders and respiratory disorders due to features like safe, efficiency and versatility. Advanced research & development facilities and new peptide developments by pharma companies are driving the demand for reasonably priced peptide therapeutics.

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Nevertheless, the large scale production of peptide with increasing complexities of peptides is a major challenge for peptide therapeutics market. The development of multifunctional peptides and rise in number of collaboration for the progress of peptide conjugates are currently ruling the market.

Latest advances in peptide synthesis technology is projected to be the key driver for the growth of peptide therapeutics industry. From among the different methods of peptide synthesis, enzymatic and chemical synthesis are important. This technology has integrated structure-activity relationships (SARs) and analog generation to increase bioavailability, increase safety & efficacy of drugs, impart protease resistance, reduce adverse effects, and develop formulations.

The other driving factor of the market is the shift towards unexploited market. The market is witnessing several vendors focusing on developing economies due to presence of large population groups and clinical trial subjects. Factors like presence of lenient regulatory guidelines, skilled labor, limited market competition, and low manufacturing costs will encourage vendors to shift their manufacturing processes to the developing economies.

Peptide therapeutics market is categorized on the basis of application, technology, route of administration, molecule type, API peptide type, and geography. On the basis of application, the market is divided into Cancer, Metabolic, CVD, Respiratory, GIT, Anti-infective, Dermatology, CNS, Renal, etc. In terms of route of administration, the market is segmented as Parenteral, Oral, etc.

On the basis of type, peptide therapeutics industry is divided into Innovative and Generic. On the basis of technology, the market is classified into Liquid Phase, Solid Phase, and Hybrid Phase. Type of Molecule is classified into Vasopressin, Somatostatin, Calcitonin, Immunopeptide, Natriuretic, and others. On the basis of API Peptide Type, the market is divided into In-house, and CMO (contract manufacturing organization).

Geographically, peptide therapeutics market is segmented as North America, Latin America, Europe, Asia Pacific, and Middle East & Africa. North America and Latin America are predicted to hold larger share of the market owing to the rising incidences of cancer and other life-style related disorders.

The key peptide therapeutics industry players comprise AstraZeneca plc, Amgen Inc., Eli Lilly and Company, Sanofi, CordenPharma International GmbH, Teva Pharmaceutical Industries Ltd., Novartis AG, Ipsen S.A., Lonza Group Ltd., Merck & Co. Inc., F. Hoffmann-La Roche AG, Bachem Holding AG, PolyPeptide Group and Novo Nordisk A/S.

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Lactoferrin market is expected to register a healthy CAGR during the forecast period

The global lactoferrin market is anticipated to cross USD 167.9 Million by 2025 and is also expected to register a healthy CAGR during the forecast period. Lactoferrin is an iron binding found in milk. It comprises a single-chain polypeptide with dual globular lobes, particularly resilient to proteolysis. Lactoferrin is a growth factor acting as a bactericidal agent apart from being an iron-binding protein.

Lactoferrin market is driven by factors such as increasing incidences of skin disorders, technological enhancements, and constant R&D. Lactoferrin is used as a medical application in cases of health disorders with an extensive support by the government for research and development. In addition, the market growth is supported with rise in geriatric population needing medical care & attention and several enhancements in medical science. However, cheap substitutes in the form of generics are likely to affect the market growth in the forecast period.

Lactoferrin market is segmented into iron absorption, anti-inflammatory, intestinal flora protection, immune and cell stimulation and antioxidant, based on function. By Application, the market segmentation includes infant formula, food & beverages, sports and functional foods, personal care, pharmaceuticals and animal feed.

Geographical segmentation for lactoferrin industry includes North America, South America, Europe, Asia-Pacific, Middle East and Africa. Asia-Pacific regions dominate the market growth in the forecast period owing to increase in birth rate in these regions. Apart, lactoferrin finds extensive use in treatment of heart diseases and other skin related problems.

North American and European markets are likely to gain a significant growth owing to preferred and relevant use by sportspeople and fitness enthusiasts. Apart, rise in health disorders, increase in consumer awareness and technological advances are likely to trigger the market growth in the forecast period. The key players in the lactoferrin market include Metagenics, Pharming Group N.V., Ingredia S.A., MP Biomedicals, Vitalus Nutrition Inc, Glanbia Nutritionals, Prohealth, Farbest Brands and Fonterra Co-operative Group Ltd.

Market Segment:

Lactoferrin Function Outlook (Revenue, USD Million; Volume Tons, 2014 - 2025)

    • Iron absorption

    • Anti-inflammatory

    • Intestinal flora protection

    • Antibacterial

    • Immune cell stimulation

    • Antioxidant

Lactoferrin Application Outlook (Revenue, USD Million; Volume Tons, 2014 - 2025)

    • Food & beverages

    • Infant formula

    • Sports & functional food

    • Animal feed

    • Pharmaceuticals

    • Personal care products

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Proteins: Receive certain modifications to cellular membrane to function effectively

The global Protein Expression Market is anticipated to grow at a CAGR of 10.4% by 2025 and is expected to cross USD 3.0 billion in the forecast period. Protein expression could prove to be a complex process, since each protein requires intracellular milieu to significantly achieve secondary features. Proteins, on the other hand, may also receive certain modifications to cellular membrane to function effectively.

Protein expression industry is driven by factors such as rise in protein production, biologics production, and research. Rise in demand for biologics by manufacturers also propels the market growth in the forecast period. Increase in R&D activities, governments’ investments, effective mergers and acquisitions are also expected to drive the growth of protein expression market in the forecast period. On the other hand, prevalence of chronic diseases such as cancer, asthma, and arthritis are likely to add to the market growth. However, stringent regulations imposed by governing authorities for drug approvals are expected to hinder the market growth in the forecast period.

The protein expression industry is segmented as expression systems, product, application and geography. Product segmentation for protein expression market includes mammalian cell, yeast, insect, and prokaryotic. Prokaryotic expressions are anticipated to grow at a higher CAGR in the forthcoming period due to high revenue generating segment and increase in production capacity.

Application segment includes research, diagnostics, and therapeutics. “Therapeutic” segment is further sub-segmented into insulin, antibodies, growth factors, blood factors, enzymes, and interferons. “Therapeutic” application is expected to grow at an enormous CAGR in the forecast period owing to increase in production of biologics. The segment is also anticipated to grow rapidly in the forecast period due to rising popularity of therapeutic drugs over generic drugs. “Research” application is further anticipated to grow at a substantial CAGR in the forecast period due to increase in government funding and high accuracy.

Geographical segmentation for protein expression industry includes North America, Latin America, Europe, Asia-Pacific, Middle East, and Africa. North American market is expected to account for a significant market share in the forthcoming period due to rise in government investment coupled with rise in biopharmaceutical and biotechnology sector as well as presence of well-defined healthcare infrastructure.

Asia-Pacific’s protein expression market is expected to grow at a positive CAGR in the upcoming period due to availability of untapped potential opportunities. Middle Eastern and African markets are anticipated to grow at a positive CAGR in the forecast period owing to improving healthcare infrastructure and increasing base of medical professionals in these areas. The key players in the protein expression industry include Agilent Technologies, Bio-Rad Laboratories Inc, Thermo Fisher Scientific Inc, New England Biolabs, Merck KGaA, Qiagen, Promega Corporation and Takara Bio Inc.

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Head and Neck Cancer Drugs/Therapeutics Market: Rising Demand, Future Scope Forecasts, 2016 - 2022

The global Head and Neck Cancer Drugs/Therapeutics Market was valued at USD 752.5 million in 2016 and is estimated to grow significantly in the coming years owing to the development of cost-effective and innovative Head and Neck Cancer treatments. Cancers of squamous cells present in the linings of larynx, nose, salivary glands, throat, lips, and mouth cause the Head and Neck Cancers. The Head and Neck Cancer is amongst the common type of cancers. The past records reveal that every year a massive number of Head and Neck Cancers are detected globally with more than half accounting to death annually. The increasing number of Head and Neck Cancer patients and the demand for cost-efficient treatment options are helping the Head and Neck Cancer Drugs/Therapeutics Market to grow with a CAGR of 9.4%.

The most preferred therapy performed by the surgeons is the surgical therapy combined with the radiation therapy. Moreover, the present treatment options available for Head and Neck Cancer results in less chances of survival rate. The latest developments in advanced radiotherapy and chemotherapy has helped to preserve some functions of the face. The treatment for Head and Neck Cancer is a significant challenge for the surgeons since the choice of treatment differs from patient to patient and tumor location. Generally, the Head and Neck Cancers are operated with the surgery, but the complicated facial structures and functions restricts the surgical operations. However, more focus is now being given to the technological developments of new targeted molecules like gene therapy, antibody drug conjugates, monoclonal antibodies, etc. This is expected to widen the market opportunities in near future, which will fuel up the market growth.

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The market categorized on the grounds of treatment type, disease indication, end user and geography. On the grounds of treatment type, the market is distributed into Chemotherapy, Radiation Therapy, External Radiation Therapy, Internal Radiation Therapy, Surgery and Targeted Therapy. Surgery, bring the most preferred therapy choice is projected to lead the Head and Neck Cancer Drugs/Therapeutics Market in the forecast period. To prevent the reoccurrence of the cancer, the Radiation therapy is used which is expected to contribute largely to the market after the surgery. Furthermore, Chemotherapy is an assistant treatment to other therapies and therefore is expected to contribute little share in the Head and Neck Cancer Drugs/Therapeutics Market.

On the grounds of disease indication, the market is distributed into Laryngeal Cancer, Lip and Oral Cavity Cancer, Nasopharyngeal Cancer, Oropharyngeal Cancer, Salivary Gland Cancer and etc. The Lip and Oral Cavity cancer is predicted to rise globally due to growing number of people affected by lip and oral cancer. On the grounds of end user, the Head and Neck Cancer Drugs/Therapeutics Market is distributed into Hospitals, Specialty Clinics and Ambulatory Surgical Centers. Hospital is expected to contribute a comparatively larger share.

Geographically, the market is segmented as North America, Latin America, Europe, Asia Pacific and Middle East & Africa. The Head and Neck Cancer Drugs/Therapeutics Market share from North America will continue to dominate due to high prevalence high smoking rate and HPV-induced cancers. After this, Europe is expected to contribute second largest market share. The leading players in the Head and Neck Cancer Drugs/Therapeutics Industry are profiled as Merck & Co. Eli Lilly, Merck Group and Bristol-Myers Squibb, Sanofi.

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